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Priligy is an oral tablet buy priligy dapoxetine medication, which treats premature buy priligy dapoxetine ejaculation. The drug marketed by Menarini is the only tablet medication currently available which is specifically designed for this purpose. Easy to use tablet, developed especially for premature ejaculation, enables you to perform for longer. Due to the private nature of the condition, and the fact that sexual tastes vary from couple to couple, defining whether premature ejaculation (PE) is present can be troublesome. It is a normal and frequent occurrence between some heterosexual couples, for the male partner to ejaculate before the female partner has reached the point of climax. However, if the male partner consistently climaxes buy priligy dapoxetine within two minutes of penetration commencing during sex, then this might be safely described as premature ejaculation. Although it doesnt sound serious, early ejaculation can be problematic in a relationship and lead to feelings of sexual dissatisfaction. This can in turn develop into feelings of tension in couples. Premature ejaculation falls into two categories: primary and secondary. The possible causes of a particular case can vary, depending on which category the case falls. Primary premature ejaculation is that which has been consistently present from an early age, also referred to as lifelong. Some believe this may be present in an individual due to psychological factors, such as early conditioning; whereby a person trains themselves from a young age to ejaculate quickly during masturbation, in order to evade being caught. Another buy priligy dapoxetine psychological factor may be a persons upbringing or ones perception of sexual activity. Secondary PE is usually acquired, and develops buy priligy dapoxetine during a persons adult life. It may be the result of an illness such as a prostate condition, or high blood pressure, or again it may be psychological. When a man enters into a new sexual relationship, for example, emotional pressure to perform may make them more likely to ejaculate prematurely. Stress or distracting influences, unrelated to the act of sex, may also be causes. There are several self-help techniques which can help men experiencing premature ejaculation to last longer.
From Wikipedia, the free encyclopedia, jump to navigation, jump to search. Avanafil is avanafil dapoxetine a, pDE5 inhibitor approved avanafil dapoxetine for erectile dysfunction by the FDA on April 27, 2012 1 and by EMA on June 21, 2013. 2, avanafil is known by the trademark names. Stendra and, spedra and was developed by, vivus Inc. In July 2013 Vivus announced partnership with. Menarini Group, which will commercialise and promote Spedra in over 40 European countries plus Australia and New Zealand. 3, avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. 4, other similar drugs are sildenafil, tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 3045 minutes. 5, about two-thirds of the participants were able to engage in sexual activity within 15 minutes. 5, contents, synthesis edit, avanafil dapoxetine avanafil can be synthesized from a benzylamine derivative and a pyrimidine derivative:. See also edit, references edit "FDA approves Stendra for erectile dysfunction" (Press release). Food and Drug Administration (FDA). Retrieved m?releaseid775706 "avanafil, Spedra". Retrieved b Kyle, Jeffery; Brown, Dana (2013). "Avanafil for Erectile Dysfunction" (PDF). Retrieved 28 September 2013. Yamada,.; Matsuki,.; Omori,.; Kikkawa,.; 2004,.S. Patent 6,797,709 External links edit Retrieved from " p?titleAvanafil oldid ". Dapoxetine, marketed as, priligy and, westoxetin, among and other brands, is the first compound developed specially avanafil dapoxetine for the treatment of premature ejaculation (PE) in men 1864 years old. 2 3, dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. 4, as a member of the selective serotonin reuptake inhibitor (ssri) family, dapoxetine was initially created as an antidepressant. However, unlike other ssris, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant. Eli Lilly pharmaceutical company, dapoxetine was sold. Johnson Johnson in 2003 and submitted. New Drug Application to the, food and Drug Administration (FDA) for the treatment of PE in 2004. 6, dapoxetine is sold in several European and Asian countries, and in Mexico. In the US, dapoxetine has been in phase III development since 2003.